|
|
|
|
|
| Loizeau, Veronique; Menesguen, Alain. |
| A five-compartment steady-state food web model is proposed for the benthic food web leading to the dab. Three exposure pathways are considered in the description of accumulation by benthic animals: ingestion of particulate contaminants associated with either sediment or phytoplankton, and respiratory uptake of free dissolved contaminant in overlaying water. Application of the model to a simple food web in the Bay of Seine (Eastern Channel) indicates that : a) feeding is the principal route of contamination, especially for PCB which have more than four chlorine atoms in the molecule ; b) excretion and growth rates, phytoplankton lipid fraction and organic carbon content of sediment are the parameters which mostly determine the chemical bioaccumulation in... |
| Tipo: Text |
Palavras-chave: MODEL; PCB; FOOD WEB; BENTHIC INVERTEBRATES; DAB. |
| Ano: 1993 |
URL: http://archimer.ifremer.fr/doc/00100/21127/18747.pdf |
| |
|
|
| Reveillon, Damien; Abadie, Eric; Sechet, Veronique; Brient, Luc; Savar, Veronique; Bardouil, Michele; Hess, Philipp; Amzil, Zouher. |
| beta-N-methylamino-L-alanine (BMAA) is a neurotoxic non-protein amino acid suggested to be involved in neurodegenerative diseases. It was reported to be produced by cyanobacteria, but also found in edible aquatic organisms, thus raising concern of a widespread human exposure. However, the chemical analysis of BMAA and its isomers are controversial, mainly due to the lack of selectivity of the analytical methods. Using factorial design, we have optimized the chromatographic separation of underivatized analogues by a hydrophilic interaction chromatography coupled to tandem mass spectrometry (HILIC-MS/MS) method. A combination of an effective solid phase extraction (SPE) clean-up, appropriate chromatographic resolution and the use of specific mass spectral... |
| Tipo: Text |
Palavras-chave: Cyanotoxins; BMAA; DAB; AEG; HILIC-MS/MS; Cyanobacteria; Bivalve mollusks; French Mediterranean. |
| Ano: 2014 |
URL: http://archimer.ifremer.fr/doc/00245/35579/34112.pdf |
| |
|
|
| Reveillon, Damien. |
| BMAA (â-N-methylamino-L-alanine) is a non proteinogenic neurotoxic amino acid that has been associated with amyotrophic lateral sclerosis. Its analytical detection is widely debated thus the global production of BMAA by cyanobacteria is questioned. We first aimed at developing an analytical method allowing for highly selective identification of BMAA and isomers, using HILIC chromatography coupled to mass spectrometry. Then, we have cultivated and analyzed more than 50 microalgae (e.g. cyanobacteria, diatoms). Unlike DAB, one of its natural isomer, BMAA was only reported in five diatom species and cannot be accounted as a cyanotoxin anymore. In parallel, we have evaluated the presence of BMAA on the three French coasts. The presence of BMAA in different... |
| Tipo: Text |
Palavras-chave: DAB; Cyanotoxines; CL-SM/SM; Diatomées; Cyanobactéries; Bivalves; BMAA; DAB; Cyanotoxins; LC-MS/MS; Diatoms; Cyanobacteria; Bivalves. |
| Ano: 2015 |
URL: http://archimer.ifremer.fr/doc/00295/40651/39617.pdf |
| |
|
|
|
